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Nutrition Research
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Omega-3 Fatty Acids and Health
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1. Connor, W. Importance of n-3 fatty acids in health and disease. American Journal of Clinical Nutrition 71(suppl):171S-5S. 2000.
2. Watkins, B. et al. Omega-3 Polyunsaturated Fatty Acids and Skeletal Health. Experimental Biology & Medicine Vol. 226(6):485-497, 2001.
"The remarkable concurrence and agreement regarding Omega-3 fatty acids is evidenced by the several thousand papers extant in the literature (1)"
"In the past 2 decades, views about dietary Omega-3 fatty acids have moved from speculation about their functions to solid evidence that they are not only essential nutrients but also may favorably modulate many diseases (1)"
"Omega-3 Fatty acids favorably affect atherosclerosis, coronary heart disease, inflammatory disease, and perhaps even behavioral disorders (1)"
"Omega-3 Fatty acids are essential fatty acids, necessary from conception through pregnancy and infancy and, undoubtedly, throughout life (1)"
"The association of cholesterol and saturated fat with increased risk of CVD [Cardiovascular Disease] initially spurred dietary recommendations to reduce the intake of animal fat and to increase the intake of plant oils (2)."
"The ratio of Omega-6 to Omega-3 fatty acids may have increased in industrialized societies because of increased consumption of vegetable oils rich in Omega-6 fatty acids ... and reduced consumption of foods rich in Omega-3 fatty acids (1)"
"The dramatic change in food formulations has led to a greater dietary intake of plant oils such as corn, safflower, and soybean oil, which are high in linoleic acid [Omega 6], and resulted in an elevated ratio of omega-6/omega-3 (n-6/n-3) fatty acids during the 20th century (2)."
"The following is a partial list of diseases that may be prevented or ameliorated with Omega-3 fatty acids...(1)"
- Coronary heart disease and stroke
- Essential fatty acid defiency in infancy (retinal and brain development)
- Autoimmune disorders (eg, lupus and nephropathy)
- Crohn disease
- Cancers of the breast, colon, and prostate
- Mild hypertension
- Rheumatoid arthritis
"Evidence suggests that the high intake of Omega-6 with an inadequate amount of Omega-3 fatty acids in the diet contributes to the development of certain cancers and some chronic diseases, including those of the skeletal system (bone/joint diseases) (2)."
"The present dietary ratio of Omega-6/Omega-3 fatty acids may be far from the optimal recommended dietary intake of Omega-3 fatty acids to protect against chronic disease risk (2)."
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